Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.37 |
| ▸ | MTOR | P42345 | 5/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316587 | 0.88 | CSF1R (0.44) | PIK3CAMTORCSF1RMCHR1 | |
| SCHEMBL24316429 | 0.84 | CSF1R (0.40) | PIK3CAMTORKDM5AKDM4CCSF1R | |
| SCHEMBL24316440 | 0.82 | CSF1R (0.38) | PIK3CAMTORCSF1RMCHR1 | |
| SCHEMBL24316446 | 0.81 | CSF1R (0.42) | PIK3CAMTORCSF1R | |
| SCHEMBL24316426 | 0.81 | CSF1R (0.46) | CSF1RMCHR1 | |
| SCHEMBL24316588 | 0.81 | CSF1R (0.44) | PIK3CAMTORCSF1RMCHR1 | |
| SCHEMBL24316427 | 0.81 | CSF1R (0.42) | PIK3CAMTORCSF1R | |
| SCHEMBL24316434 | 0.80 | CSF1R (0.53) | PIK3CAMTORCSF1RPOLB | |
| SCHEMBL24316983 | 0.79 | CSF1R (0.46) | PIK3CAMTORCSF1RMCHR1 | |
| SCHEMBL24316982 | 0.79 | CSF1R (0.48) | PIK3CAMTORCSF1RMCHR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |
| US-9585884-B2 | Pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2017-03-07 | — | — | US | disclosed |