Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | MTOR | P42345 | 4/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316587 | 0.88 | CSF1R (0.44) | CSF1RPIK3CAMTORRXFP1MCHR1 | |
| SCHEMBL24316434 | 0.85 | CSF1R (0.53) | CSF1RPIK3CAMTORALKBH1RXFP1 | |
| SCHEMBL24316546 | 0.85 | CSF1R (0.42) | CSF1RRXFP1MCHR1 | |
| SCHEMBL24316982 | 0.84 | CSF1R (0.48) | CSF1RPIK3CAMTORALKBH1RXFP1 | |
| SCHEMBL24316441 | 0.84 | PIK3CA (0.37) | CSF1RPIK3CAMTORKDM5AKDM4C | |
| SCHEMBL24316814 | 0.83 | CSF1R (0.47) | CSF1RPIK3CAMTORRXFP1MCHR1 | |
| SCHEMBL24316446 | 0.83 | CSF1R (0.42) | CSF1RPIK3CAMTORALKBH1RXFP1 | |
| SCHEMBL24316983 | 0.83 | CSF1R (0.46) | CSF1RPIK3CAMTORALKBH1RXFP1 | |
| SCHEMBL24316551 | 0.82 | GRM5 (0.49) | CSF1RALKBH1GRM5P2RX7 | |
| SCHEMBL24316427 | 0.82 | CSF1R (0.42) | CSF1RPIK3CAMTORALKBH1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |