Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316661 | 0.94 | CSF1R (0.52) | CSF1RRXFP1KITPIK3CAMTOR | |
| SCHEMBL24316982 | 0.93 | CSF1R (0.48) | CSF1RRXFP1POLBKITGRM5 | |
| SCHEMBL24316588 | 0.89 | CSF1R (0.44) | CSF1RPIK3CAMTORMCHR1 | |
| SCHEMBL24316434 | 0.88 | CSF1R (0.53) | CSF1RRXFP1POLBKITGRM5 | |
| SCHEMBL24316658 | 0.87 | CSF1R (0.42) | CSF1RRXFP1GRM5KDM4EP2RX3 | |
| SCHEMBL24316546 | 0.86 | CSF1R (0.42) | CSF1RRXFP1POLBKITMAOA | |
| SCHEMBL24316550 | 0.86 | CSF1R (0.43) | CSF1RKITGRM5PIK3CAMTOR | |
| SCHEMBL24316814 | 0.85 | CSF1R (0.47) | CSF1RRXFP1GRM5KDM4EPIK3CA | |
| SCHEMBL24316983 | 0.85 | CSF1R (0.46) | CSF1RRXFP1GRM5PIK3CAMTOR | |
| SCHEMBL24316448 | 0.84 | CSF1R (0.45) | CSF1RRXFP1POLBGRM5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |