Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316622 | 0.94 | CYP11B1 (0.39) | CSF1RRXFP1PIK3CAMTORCYP11B1 | |
| SCHEMBL24316620 | 0.91 | CSF1R (0.37) | CSF1RRXFP1PIK3CAMTORALDH1A1 | |
| SCHEMBL24316434 | 0.90 | CSF1R (0.53) | CSF1RRXFP1PIK3CAMTORKDM4E | |
| SCHEMBL24316621 | 0.87 | PIK3CA (0.38) | CSF1RRXFP1PIK3CAMTORKDM4E | |
| SCHEMBL24316982 | 0.86 | CSF1R (0.48) | CSF1RRXFP1PIK3CAMTORKDM4E | |
| SCHEMBL24316814 | 0.84 | CSF1R (0.47) | CSF1RRXFP1PIK3CAMTORKDM4E | |
| SCHEMBL24316983 | 0.84 | CSF1R (0.46) | CSF1RRXFP1PIK3CAMTORALDH1A1 | |
| SCHEMBL24316448 | 0.83 | CSF1R (0.45) | CSF1RRXFP1PIK3CAMTORPDE1A | |
| SCHEMBL24316545 | 0.82 | CSF1R (0.43) | CSF1RRXFP1PIK3CAMTORKDM4E | |
| SCHEMBL24316661 | 0.82 | CSF1R (0.52) | CSF1RRXFP1PIK3CAMTORPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |