Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316658 | 0.93 | CSF1R (0.42) | CSF1RALKBH1TLR8GRM5KDM4E | |
| SCHEMBL24316434 | 0.92 | CSF1R (0.53) | CSF1RALKBH1PIK3CAMTORGRM5 | |
| SCHEMBL24316565 | 0.91 | CSF1R (0.44) | CSF1RALKBH1PIK3CAMTORGRM5 | |
| SCHEMBL24316660 | 0.89 | CSF1R (0.40) | CSF1RALKBH1PIK3CAMTORGRM5 | |
| SCHEMBL24316982 | 0.87 | CSF1R (0.48) | CSF1RALKBH1PIK3CAMTORGRM5 | |
| SCHEMBL24316659 | 0.86 | ALKBH1 (0.40) | CSF1RALKBH1GRM5KDM4EALDH1A1 | |
| SCHEMBL24316814 | 0.85 | CSF1R (0.47) | CSF1RPIK3CAMTORGRM5KDM4E | |
| SCHEMBL24316428 | 0.85 | ALKBH1 (0.39) | CSF1RALKBH1GRM5KDM4EALDH1A1 | |
| SCHEMBL24316983 | 0.85 | CSF1R (0.46) | CSF1RALKBH1PIK3CAMTORTLR8 | |
| SCHEMBL24316448 | 0.84 | CSF1R (0.45) | CSF1RPIK3CAMTORGRM5PDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |