Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316550 | 0.93 | CSF1R (0.43) | CSF1RKITHCRTR1HCRTR2PIK3CA | |
| SCHEMBL24317042 | 0.91 | CSF1R (0.39) | CSF1RKITHCRTR1HCRTR2PIK3CA | |
| SCHEMBL24316434 | 0.87 | CSF1R (0.53) | CSF1RKITPIK3CAMTORRXFP1 | |
| SCHEMBL24316982 | 0.86 | CSF1R (0.48) | CSF1RKITPIK3CAMTORRXFP1 | |
| SCHEMBL24316983 | 0.86 | CSF1R (0.46) | CSF1RPIK3CAMTORRXFP1 | |
| SCHEMBL24316814 | 0.85 | CSF1R (0.47) | CSF1RPIK3CAMTORRXFP1 | |
| SCHEMBL24316448 | 0.83 | CSF1R (0.45) | CSF1RPIK3CAMTORRXFP1 | |
| SCHEMBL24316437 | 0.82 | CSF1R (0.45) | CSF1RPIK3CAMTORRXFP1 | |
| SCHEMBL24316587 | 0.82 | CSF1R (0.44) | CSF1RPIK3CAMTORRXFP1 | |
| SCHEMBL24316553 | 0.82 | CSF1R (0.46) | CSF1RPIK3CAMTORRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022057895-A1 | HETEROAROMATIC COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2022-03-24 | — | — | WO | disclosed |