Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20006780 | 0.81 | DRD2 (0.53) | HTR1DKCNH2DRD2ADRB2ADRB1 | |
| SCHEMBL24317011 | 0.80 | DRD2 (0.46) | HTR1DHTR1BDRD2ADRA1AHTR1A | |
| SCHEMBL20006880 | 0.77 | HTR1D (0.45) | HTR1DHTR1BKCNH2DRD2ADRB2 | |
| SCHEMBL24317059 | 0.75 | HTR1D (0.49) | HTR1DHTR1BKCNH2TMEM97SIGMAR1 | |
| SCHEMBL14240235 | 0.74 | ADRB2 (0.68) | HTR1DHTR1BKCNH2TMEM97DRD2 | |
| SCHEMBL23940661 | 0.72 | HTR1D (0.48) | HTR1DHTR1BKCNH2TMEM97SIGMAR1 | |
| SCHEMBL20006770 | 0.71 | HTR1D (0.52) | HTR1DHTR1BKCNH2TMEM97SIGMAR1 | |
| SCHEMBL19174337 | 0.70 | ADRB2 (0.45) | HTR1DHTR1BKCNH2TMEM97DRD2 | |
| SCHEMBL19174286 | 0.70 | ADRB2 (0.45) | HTR1DHTR1BKCNH2TMEM97DRD2 | |
| SCHEMBL20007103 | 0.70 | HTR1A (0.44) | HTR1DKCNH2DRD2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |