Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975696 | 0.88 | DRD2 (0.62) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL26268651 | 0.87 | ABHD6 (0.52) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL5568684 | 0.81 | DRD1 (0.77) | DRD2DRD3DRD1DRD5 | |
| SCHEMBL27010059 | 0.78 | DRD2 (0.54) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL19957848 | 0.77 | ALDH1A1 (0.44) | DRD2DRD3DRD1DRD5ALDH1A1 | |
| SCHEMBL23976082 | 0.77 | DRD1 (0.76) | DRD2DRD3DRD1DRD5 | |
| SCHEMBL14067213 | 0.76 | PDE4D (0.59) | DRD2DRD3DRD1DRD5CHRM2 | |
| SCHEMBL30641865 | 0.75 | DRD2 (0.51) | DRD2DRD3DRD1DRD5ABHD6 | |
| SCHEMBL5452590 | 0.75 | DRD2 (0.51) | DRD2DRD3DRD1DRD5ALDH1A1 | |
| SCHEMBL14067047 | 0.75 | NOTUM (0.58) | DRD2DRD3DRD1DRD5ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |