Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | SELE | P16581 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364087 | 0.81 | ADH5 (0.75) | ADH5CYP3A4HTTBAZ2BHTR2A | |
| SCHEMBL22437049 | 0.81 | ADH5 (0.53) | ADH5CYP3A4CYP19A1HTTBAZ2B | |
| SCHEMBL30900589 | 0.81 | ADH5 (0.53) | ADH5CYP3A4CYP19A1HTTBAZ2B | |
| SCHEMBL10512975 | 0.78 | LMNA (0.62) | CYP3A4CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL21940149 | 0.76 | CYP3A4 (0.62) | ADH5CYP3A4CYP2D6ICAM1SELE | |
| SCHEMBL4365227 | 0.76 | KDM4E (0.49) | ALDH1A1 | |
| SCHEMBL22737610 | 0.76 | GCK (0.54) | ALDH1A1 | |
| SCHEMBL7005980 | 0.76 | CYP3A4 (0.69) | CYP3A4CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL4334161 | 0.75 | ALDH1A1 (0.47) | CYP3A4ALDH1A1 | |
| SCHEMBL2427202 | 0.75 | P2RX3 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117254-A1 | PIPERIDINE AMIDES AS MODULATORS OF THE GHRELIN RECEPTOR | PROSIDION LIMITED (GB) | 2011-09-29 | — | — | WO | disclosed |