Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24321350 | 0.89 | MEN1 (0.47) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL24321184 | 0.88 | HSP90AA1 (0.46) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL24321134 | 0.82 | HSP90AA1 (0.47) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL16569200 | 0.82 | KDM4E (0.42) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL18561685 | 0.82 | HSP90AA1 (0.40) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL24321700 | 0.80 | HSP90AA1 (0.44) | KDM4EALDH1A1TDP1HSP90AA1HSP90B1 | |
| SCHEMBL24321302 | 0.79 | HSP90AA1 (0.42) | HSP90AA1MAPK1HSP90B1TRAP1 | |
| SCHEMBL22541300 | 0.79 | HSP90AA1 (0.40) | KDM4EALDH1A1TDP1HSP90AA1HSP90B1 | |
| SCHEMBL24321211 | 0.78 | ALDH1A1 (0.42) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL16569651 | 0.78 | HSP90AA1 (0.44) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078414-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |