Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973523 | 0.86 | SIGMAR1 (1.00) | SIGMAR1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11071000 | 0.78 | KDM4E (0.65) | SIGMAR1ALDH1A1GAAEPHX1KDM4E | |
| SCHEMBL6678936 | 0.77 | SIGMAR1 (0.58) | SIGMAR1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL11060305 | 0.75 | SIGMAR1 (0.57) | SIGMAR1KMT2AMEN1EPHX1KDM4E | |
| SCHEMBL13581 | 0.74 | EPHX1 (0.55) | KMT2AMEN1ALDH1A1GAAEPHX1 | |
| SCHEMBL19652274 | 0.74 | EPHX1 (0.55) | KMT2AMEN1ALDH1A1GAAEPHX1 | |
| SCHEMBL11066538 | 0.74 | SIGMAR1 (0.63) | SIGMAR1KMT2AMEN1KDM4ETSHR | |
| SCHEMBL7748187 | 0.74 | SIGMAR1 (0.56) | SIGMAR1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL11063231 | 0.73 | SIGMAR1 (0.54) | SIGMAR1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL977989 | 0.73 | KDM4E (0.58) | SIGMAR1ALDH1A1GAAEPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | SIGMAR1 3622/4885KMT2A 3149/4885MEN1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.