SCHEMBL24322786

SCHEMBL24322786

CC1CCN(CCNC(=O)[C@H]2CCCNC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
HTT P42858 2/20 0.44
CARM1 Q86X55 1/20 0.43
PRMT6 Q96LA8 1/20 0.43
PRMT1 Q99873 1/20 0.43
PRMT8 Q9NR22 1/20 0.43
ALOX15 P16050 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
SLC6A1 P30531 2/20 0.41
SLC6A11 P48066 1/20 0.41
TSHR P16473 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLC6A13 Q9NSD5 1/20 0.41
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
GNAI3 P08754 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24323696 0.84 ALDH1A1 (0.56) ALDH1A1L3MBTL1TSHRSMN1; SMN2KMT2A
SCHEMBL2146920 0.82 ALOX15 (0.50) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
SCHEMBL30587419 0.81 SMN1; SMN2 (0.54) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
Hydrochloric Acid SCHEMBL2145967 0.81 ALOX15 (0.49) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
SCHEMBL2146242 0.81 ALOX15 (0.49) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
Hydrochloric Acid SCHEMBL2145957 0.81 ALOX15 (0.49) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
SCHEMBL10030564 0.80 SLC6A1 (0.57) ALOX15SLC6A1SLC6A11TSHRLMNA
Hydrochloric Acid SCHEMBL2146418 0.80 ALOX15 (0.48) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
Hydrochloric Acid SCHEMBL2146412 0.80 ALOX15 (0.48) ALDH1A1ALOX15L3MBTL1ITGB3ITGA2B
SCHEMBL13285080 0.77 CHRNB2 (0.57) ALDH1A1SLC6A1SLC6A11TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof Psomagen Inc. (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof HTRA1, GIPR, HPN ALDH1A1 4556/4885HTT 70/4885CARM1 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.