Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180605 | 0.84 | KMT2A (0.68) | KMT2ATSHRMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL10947749 | 0.84 | KMT2A (0.76) | KMT2ATSHRMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL21788565 | 0.82 | SMN1; SMN2 (0.57) | KMT2AMEN1ALDH1A1L3MBTL1CYP2C19 | |
| SCHEMBL5080239 | 0.82 | KMT2A (0.78) | KMT2ATSHRMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL24324292 | 0.81 | KHK (0.61) | KMT2AMEN1ALDH1A1L3MBTL1POLB | |
| SCHEMBL9763185 | 0.79 | SLC6A1 (0.59) | KMT2ATSHRALDH1A1L3MBTL1KDM4E | |
| Bromide SCHEMBL9763700 | 0.78 | SLC6A1 (0.57) | KMT2ATSHRALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8917273 | 0.78 | KDM4E (0.66) | KMT2ATSHRMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL24322564 | 0.77 | HSD11B1 (0.67) | KMT2ATSHRALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1945424 | 0.77 | ALDH1A1 (0.51) | KMT2ATSHRMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | HTRA1, GIPR, HPN | KMT2A 3149/4885TSHR 1902/4885MEN1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.