Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.57 |
| ▸ | EBP | Q15125 | 3/20 | 0.57 |
| ▸ | DHCR7 | Q9UBM7 | 3/20 | 0.57 |
| ▸ | ESRRB | O95718 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ESRRG | P62508 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851091 | 0.89 | ESR1 (0.65) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL23851093 | 0.89 | ESR1 (0.65) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL24322411 | 0.89 | ESR1 (0.65) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL24322285 | 0.87 | ESR1 (0.58) | ESR1ESRRBMEN1KMT2ADRD2 | |
| SCHEMBL15788563 | 0.83 | ESR1 (0.79) | ESR1ESR2EBPDHCR7MAPT | |
| SCHEMBL17164697 | 0.80 | ESR1 (0.89) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL17164708 | 0.80 | ESR1 (0.89) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL18872440 | 0.78 | ESR1 (0.81) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL10829107 | 0.78 | ESR1 (1.00) | ESR1ESR2EBPDHCR7ESRRB | |
| SCHEMBL10048291 | 0.78 | ESR1 (1.00) | ESR1ESR2EBPDHCR7ESRRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220089600-A1 | TGFß INHIBITOR AND PRODRUGS | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089600-A1 | TGFß INHIBITOR AND PRODRUGS | TGFB1, TGFBR1, TGFBR2 | ESR1 2521/4885ESR2 876/4885EBP 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.