Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239442 | 0.85 | L3MBTL1 (0.55) | L3MBTL1MEN1KMT2AHTTSIGMAR1 | |
| Hydrochloric Acid SCHEMBL1242121 | 0.84 | MEN1 (0.58) | L3MBTL1MEN1KMT2ASIGMAR1APP | |
| SCHEMBL2687056 | 0.79 | SIGMAR1 (0.59) | L3MBTL1MEN1KMT2ASIGMAR1APP | |
| SCHEMBL24010593 | 0.79 | HTT (0.51) | L3MBTL1MEN1KMT2AHTTHDAC3 | |
| SCHEMBL1650495 | 0.78 | CA2 (0.47) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL123966 | 0.76 | CA2 (0.45) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL12464629 | 0.75 | CNR2 (0.50) | L3MBTL1 | |
| SCHEMBL23640939 | 0.75 | L3MBTL1 (0.44) | L3MBTL1MEN1KMT2AHTTSIGMAR1 | |
| SCHEMBL16081620 | 0.75 | ATM (0.54) | L3MBTL1MEN1KMT2AHTTSIGMAR1 | |
| SCHEMBL10663744 | 0.74 | GAA (0.40) | L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076625-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |