Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327928 | 0.81 | HKDC1 (0.49) | LMNAMAPTTHRBL3MBTL1KDM4E | |
| SCHEMBL4346341 | 0.74 | GAA (0.70) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL24328014 | 0.71 | OXTR (0.42) | LMNAMAPTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL4347137 | 0.71 | GAA (0.69) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL17653296 | 0.71 | GAA (1.00) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL4359794 | 0.71 | GAA (0.57) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL4345493 | 0.70 | GAA (0.60) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL4347345 | 0.69 | GAA (0.67) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL4348998 | 0.69 | MAPT (0.70) | GAALMNAMAPTTHRBL3MBTL1 | |
| SCHEMBL24327531 | 0.69 | MAPT (0.47) | GAAMAPTL3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |