Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | HK1 | P19367 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 6/20 | 0.44 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328014 | 0.85 | OXTR (0.42) | HKDC1KMT2ARAB9AAPAF1HK1 | |
| SCHEMBL9750769 | 0.84 | HKDC1 (0.60) | HKDC1NSD2HSP90AA1G6PDCCR6 | |
| SCHEMBL24327531 | 0.82 | MAPT (0.47) | KMT2ARAB9AMAPTHTTMEN1 | |
| SCHEMBL24327534 | 0.82 | FFAR1 (0.41) | CA1CA2CA12KDM4E | |
| SCHEMBL24327491 | 0.81 | GAA (0.54) | KMT2AMAPTLMNAHTTMEN1 | |
| SCHEMBL2466820 | 0.78 | NSD2 (0.71) | HKDC1NSD2HSP90AA1G6PDCCR6 | |
| SCHEMBL11220891 | 0.78 | MAPT (0.59) | HKDC1NSD2CCR6KMT2ARAB9A | |
| SCHEMBL24327493 | 0.74 | CDC25A (0.42) | HKDC1NSD2HSP90AA1G6PDCCR6 | |
| SCHEMBL24327529 | 0.74 | MAPT (0.47) | HKDC1NSD2HSP90AA1G6PDCCR6 | |
| SCHEMBL24327930 | 0.73 | MAPT (0.46) | NSD2HSP90AA1RAB9AAPAF1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |