Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 7/20 | 0.35 |
| ▸ | TYK2 | P29597 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 6/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 3/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327399 | 0.88 | AHR (0.41) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327880 | 0.88 | CNR1 (0.40) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327337 | 0.82 | JAK2 (0.39) | CNR1CNR2JAK2TYK2CYP3A4 | |
| SCHEMBL24328756 | 0.77 | CNR1 (0.39) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327878 | 0.76 | EPHB4 (0.42) | JAK2TYK2JAK1JAK3 | |
| SCHEMBL24328753 | 0.76 | IRAK1 (0.42) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327400 | 0.75 | AHR (0.41) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327363 | 0.74 | TTK (0.39) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327395 | 0.73 | JAK2 (0.44) | CNR1CNR2CHEK1JAK2TYK2 | |
| SCHEMBL24327391 | 0.72 | JAK2 (0.39) | CNR1CNR2CHEK1JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |