Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | DNM2 | P50570 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417295 | 0.94 | ALDH1A1 (0.47) | ALDH1A1ABL1PLK1 | |
| SCHEMBL14377111 | 0.79 | ALDH1A1 (0.69) | ALDH1A1ABL1PLK1EPHX2L3MBTL1 | |
| SCHEMBL21017598 | 0.79 | ALDH1A1 (0.69) | ALDH1A1ABL1PLK1EPHX2L3MBTL1 | |
| SCHEMBL7764821 | 0.77 | ALDH1A1 (0.71) | ALDH1A1ABL1PLK1EPHX2L3MBTL1 | |
| SCHEMBL5003764 | 0.76 | ABL1 (0.54) | ALDH1A1ABL1PLK1EPHX2DNM2 | |
| SCHEMBL28412187 | 0.76 | PLK1 (0.55) | ALDH1A1PLK1 | |
| SCHEMBL27494174 | 0.75 | ALDH1A1 (0.55) | ALDH1A1ABL1PLK1EPHX2PNLIP | |
| SCHEMBL205604 | 0.75 | ABL1 (0.56) | ALDH1A1ABL1PLK1EPHX2PRSS1 | |
| SCHEMBL10406890 | 0.75 | ABL1 (0.56) | ALDH1A1ABL1PLK1EPHX2PRSS1 | |
| SCHEMBL8445104 | 0.73 | PNLIP (0.55) | ALDH1A1ABL1PLK1PNLIPEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068933-A1 | COMPOUNDS AND METHODS OF TREATING DISEASES | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-07 | — | — | WO | disclosed |