Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327526 | 0.83 | DHODH (0.54) | MAPTP2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL12283415 | 0.83 | MAPT (0.61) | MAPTNPC1HTTRAB9AMAPK1 | |
| SCHEMBL24327534 | 0.81 | FFAR1 (0.41) | AKT1P2RX1CA1CA2EPHX2 | |
| SCHEMBL15906860 | 0.80 | MAPT (0.58) | MAPTNPC1HTTRAB9AMAPK1 | |
| SCHEMBL24328015 | 0.80 | TOP2A (0.48) | MAPTNPC1HTTRAB9AMAPK1 | |
| SCHEMBL11220891 | 0.80 | MAPT (0.59) | MAPTNPC1HTTRAB9AMAPK1 | |
| SCHEMBL24327929 | 0.78 | MAPT (0.51) | MAPTNPC1HTTRAB9AMAPK1 | |
| SCHEMBL24327488 | 0.72 | DHODH (0.54) | MAPTP2RX1P2RX4P2RX7NPC1 | |
| SCHEMBL24327533 | 0.70 | MAPT (0.44) | AKT1MAPTNPC1HTTRAB9A | |
| SCHEMBL197302 | 0.69 | GPR55 (0.55) | MAPTTP53NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081984-A1 | METHODS AND COMPOUNDS TO TREAT SARS INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-21 | — | — | WO | disclosed |