SCHEMBL24328239

SCHEMBL24328239

CO[C@@H](Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.59
PPARA Q07869 11/20 0.59
PPARD Q03181 5/20 0.55
SRR Q9GZT4 4/20 0.50
PSAT1 Q9Y617 2/20 0.49
MMP1 P03956 1/20 0.48
CPA1 P15085 1/20 0.47
LDHA P00338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14392283 0.88 PPARA (0.64) PPARGPPARAPPARDCPA1
SCHEMBL5385471 0.88 PPARA (0.74) PPARGPPARAPPARD
SCHEMBL5395182 0.85 PPARA (0.81) PPARGPPARAPPARD
SCHEMBL3466702 0.84 PPARA (0.56) PPARGPPARAPPARDSRRPSAT1
SCHEMBL4451311 0.84 PPARA (0.56) PPARGPPARAPPARDSRRPSAT1
SCHEMBL4941128 0.84 PPARA (0.56) PPARGPPARAPPARDSRRPSAT1
SCHEMBL2517934 0.83 SRR (0.70) PPARGPPARAPPARDSRRPSAT1
SCHEMBL16877217 0.83 SRR (0.70) PPARGPPARAPPARDSRRPSAT1
SCHEMBL9628212 0.83 SRR (0.70) PPARGPPARAPPARDSRRPSAT1
SCHEMBL24328379 0.83 PPARA (0.66) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
WO-2022078416-A1 NOVEL GLUTAMINE ANALOGS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS PPARG 1211/4885PPARA 1857/4885PPARD 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.