SCHEMBL24328344

SCHEMBL24328344

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C3=NC4=NC(c5ccc(N(c6ccc(C)cc6)c6ccc(C)cc6)cc5)=NC5=NC(c6ccc(N(c7ccc(C)cc7)c7ccc(C)cc7)cc6)=NC(=N3)N45)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
APP P05067 1/20 0.31
KMT2A Q03164 2/20 0.31
POLB P06746 1/20 0.31
NOTUM Q6P988 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NISCH Q9Y2I1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623766 0.89 TDP1 (0.36) ALDH1A1TSHRKMT2APOLBNOTUM
SCHEMBL20779850 0.84 ALDH1A1 (0.41) ALDH1A1APPKMT2AMEN1CYP1A2
SCHEMBL27344843 0.82 PTGDR2 (0.32) POLBNPC1RAB9ASMN1; SMN2
SCHEMBL26576296 0.82 HSD11B1 (0.47) NPC1RAB9ANISCH
SCHEMBL21477273 0.82 HSD11B1 (0.47) NPC1RAB9ANISCH
SCHEMBL16382111 0.81 KIF11 (0.38) ALDH1A1TSHRKMT2APOLBMEN1
SCHEMBL26077595 0.80 ACHE (0.48) TSHRAPPKMT2AMEN1NPC1
SCHEMBL27344931 0.78
SCHEMBL26043022 0.76 MAPT (0.33) ALDH1A1TSHRKMT2AMEN1MAPT
SCHEMBL2623732 0.76 ALDH1A1 (0.38) ALDH1A1TSHRNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230119624-A1 COMPOSITION, FILM, ORGANIC LIGHT EMITTING ELEMENT, METHOD FOR PROVIDING LIGHT EMITTING COMPOSITION, AND PROGRAM KYULUX, INC. (JP) 2023-04-20 US disclosed
EP-4102587-A1 COMPOSITION, FILM, ORGANIC LIGHT EMITTING ELEMENT, METHOD FOR PROVIDING LIGHT EMITTING COMPOSITION, AND PROGRAM Kyulux, Inc. (JP) 2022-12-14 EP disclosed
EP-4102588-A1 HOST MATERIAL, COMPOSITION, AND ORGANIC ELECTROLUMINESCENT ELEMENT Kyulux, Inc. (JP) 2022-12-14 EP disclosed
US-20220123249-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119624-A1 COMPOSITION, FILM, ORGANIC LIGHT EMITTING ELEMENT, METHOD FOR PROVIDING LIGHT EMITTING COMPOSITION, AND PROGRAM SOS1, MLLT1, ESYT2 ALDH1A1 1488/4885TSHR 4200/4885APP 649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.