Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14591313 | 0.81 | ALOX12 (0.47) | MEN1KMT2ACYP11B1CYP11B2POLB | |
| SCHEMBL24327585 | 0.80 | CYP11B1 (0.38) | MEN1KMT2ACYP11B1CYP11B2POLB | |
| SCHEMBL14591407 | 0.74 | HTR6 (0.50) | — | |
| SCHEMBL23181523 | 0.73 | DRD2 (0.41) | MEN1KMT2ANOTUMHPGDMAPT | |
| SCHEMBL14591325 | 0.72 | ALOX12 (0.56) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL2102471 | 0.72 | KMT2A (0.58) | MEN1KMT2ACYP11B1CYP11B2POLB | |
| SCHEMBL30833729 | 0.71 | CES1 (0.45) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL29190645 | 0.71 | CES1 (0.45) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL19603146 | 0.70 | RAB9A (0.41) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL24328575 | 0.68 | ALOX12 (0.44) | MEN1KMT2APOLBTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063106-A1 | INDOLINE COMPOUNDS AND DERIVATIVES AS EGFR INHIBITORS | BEIGENE, LTD. (KY) | 2022-03-31 | — | — | WO | disclosed |