Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322169 | 0.87 | — | — | |
| SCHEMBL29974712 | 0.87 | — | — | |
| SCHEMBL62868 | 0.87 | — | — | |
| SCHEMBL998929 | 0.87 | — | — | |
| SCHEMBL2803613 | 0.87 | — | — | |
| SCHEMBL700196 | 0.87 | — | — | |
| SCHEMBL11243524 | 0.75 | — | — | |
| SCHEMBL2193688 | 0.75 | — | — | |
| SCHEMBL2833653 | 0.75 | — | — | |
| SCHEMBL3287966 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242068-B1 | Solid state pulse therapy capacitor | CARDIAC PACEMAKERS INC (US) | 2011-09-14 | — | — | EP | disclosed |
| EP-2242068-A1 | Solid state pulse therapy capacitor | CARDIAC PACEMAKERS, INC. (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-2122640-B1 | SOLID STATE PULSE THERAPY CAPACITOR | CARDIAC PACEMAKERS INC (US) | 2010-04-28 | — | — | EP | disclosed |
| EP-2122640-A1 | SOLID STATE PULSE THERAPY CAPACITOR | Cardiac Pacemakers, Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008076159-A1 | SOLID STATE PULSE THERAPY CAPACITOR | CARDIAC PACEMAKERS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |