Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.39 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | NPY4R | P50391 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.38 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | ADAM8 | P78325 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810892 | 0.89 | SIRT2 (0.41) | SIRT2SIRT1SIRT3SIRT5C3AR1 | |
| SCHEMBL20043710 | 0.88 | SIRT2 (0.46) | SIRT2SIRT1ITGB3ITGA2BSIRT3 | |
| SCHEMBL17683439 | 0.87 | SIRT2 (0.45) | SIRT2SIRT1ITGB3ITGA2BSIRT3 | |
| SCHEMBL23347054 | 0.87 | SIRT2 (0.45) | SIRT2SIRT1ITGB3ITGA2BSIRT3 | |
| SCHEMBL19633304 | 0.87 | SPHK1 (0.41) | SIRT2SIRT1SIRT3SIRT5C3AR1 | |
| SCHEMBL21883411 | 0.86 | SIRT2 (0.39) | SIRT2SIRT1SIRT3NPY1RNPY4R | |
| SCHEMBL23189264 | 0.86 | ITGB3 (0.42) | SIRT2SIRT1ITGB3ITGA2BNPY1R | |
| SCHEMBL19681568 | 0.86 | ITGB3 (0.42) | SIRT2SIRT1ITGB3ITGA2BNPY1R | |
| SCHEMBL21205432 | 0.86 | SIRT2 (0.48) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL18431308 | 0.85 | FURIN (0.41) | SIRT2SIRT1SIRT3SIRT5ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11697690-B2 | Site-specific glycoengineering of targeting moieties | GENZYME CORPORATION (US) | 2023-07-11 | — | — | US | disclosed |
| US-20220119547-A1 | SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES | GENZYME CORPORATION | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119547-A1 | SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES | CD2BP2, CD74, ENGASE | SIRT2 4451/4885SIRT1 4420/4885ITGB3 402/4885 |
| US-11697690-B2 | Site-specific glycoengineering of targeting moieties | CD2BP2, CD74, ENGASE | SIRT2 4451/4885SIRT1 4420/4885ITGB3 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.