SCHEMBL24329186

SCHEMBL24329186

CC(=O)N1NC(=C2C(=O)N(C)C(=O)N(C)C2=O)CC1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.37
EGFR P00533 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
UBE2N P61088 1/20 0.35
POLB P06746 1/20 0.35
KIF11 P52732 5/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ATM Q13315 1/20 0.35
RIPK1 Q13546 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564282 0.94 ACHE (0.41) NT5E
SCHEMBL24329761 0.90 FFAR1 (0.38) NPC1RAB9AKMT2AALDH1A1ATM
SCHEMBL24329162 0.89 MAOA (0.39) EGFRNPC1RAB9AALDH1A1
SCHEMBL24329753 0.88 NT5E (0.38) NT5EEGFRKDM4EALDH1A1
SCHEMBL24329668 0.88 RIPK1 (0.41) KMT2ATSHRALDH1A1ATMRIPK1
SCHEMBL24328739 0.88 MAOA (0.40) EGFRNPC1RAB9AKMT2AKDM4E
SCHEMBL24329750 0.87 KDM4E (0.39) KMT2AKDM4ETSHRATMRIPK1
SCHEMBL24329733 0.86 ACHE (0.44) EGFRKMT2A
SCHEMBL29564283 0.85 RIPK1 (0.36) KDM4EKIF11ALDH1A1ATMRIPK1
SCHEMBL24328742 0.82 ELANE (0.36) KMT2APOLBTSHRALDH1A1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022080346-A1 NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF 国立大学法人佐賀大学 2022-04-21 WO disclosed
WO-2022080346-A1 NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF 国立大学法人佐賀大学 2022-04-21 WO disclosed