Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.65 |
| ▸ | KDM4A | O75164 | 1/20 | 0.65 |
| ▸ | KDM4B | O94953 | 1/20 | 0.65 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24329676 | 0.86 | MAPT (0.53) | L3MBTL1KDM4EALDH1A1HTTLMNA | |
| SCHEMBL18997288 | 0.85 | ADORA3 (0.82) | L3MBTL1KDM4EALDH1A1HTTLMNA | |
| SCHEMBL24330744 | 0.82 | PARP1 (0.57) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL26884220 | 0.82 | SMN1; SMN2 (0.48) | L3MBTL1KDM4EALDH1A1HTTLMNA | |
| SCHEMBL26884178 | 0.82 | KMT2A (0.47) | L3MBTL1KDM4EALDH1A1HTTLMNA | |
| SCHEMBL26658235 | 0.79 | LMNA (0.59) | KDM4EALDH1A1HTTLMNAKMT2A | |
| SCHEMBL26884172 | 0.78 | MEN1 (0.54) | KDM4EALDH1A1HTTLMNAKMT2A | |
| SCHEMBL26884180 | 0.78 | KMT2A (0.61) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL17716927 | 0.78 | ALDH1A1 (0.75) | L3MBTL1KDM4EALDH1A1HTTLMNA | |
| SCHEMBL18997291 | 0.77 | L3MBTL1 (0.67) | L3MBTL1KDM4EALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | CARTHRONIX INC (US) | 2023-11-30 | — | — | US | disclosed |
| WO-2022082071-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF US THEREOF | CARTHRONIX, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382903-A1 | SMALL MOLECULE MODULATORS OF GP130 SIGNALING PATHWAYS, TOPICAL FORMULATIONS AND METHOD OF USE THEREOF | STAT1, STAT3, STAT6 | L3MBTL1 4645/4885KDM4E 4225/4885ALDH1A1 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.