Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2427378 | 1.00 | KMT2A (0.44) | KMT2ALMNAMEN1KDM4ETSHR | |
| SCHEMBL12295624 | 0.91 | HTT (0.41) | KMT2ALMNAMEN1KDM4ETSHR | |
| SCHEMBL2427480 | 0.90 | EPHX2 (0.42) | TRPM8EPHX2TRPV1 | |
| SCHEMBL2427211 | 0.90 | EPHX2 (0.42) | TRPM8EPHX2TRPV1 | |
| SCHEMBL2342831 | 0.89 | KMT2A (0.47) | KMT2ALMNAMEN1KDM4ETSHR | |
| SCHEMBL3353050 | 0.83 | KMT2A (0.50) | KMT2ALMNAMEN1KDM4ETSHR | |
| SCHEMBL3353056 | 0.83 | KMT2A (0.50) | KMT2ALMNAMEN1KDM4ETSHR | |
| SCHEMBL2424231 | 0.83 | KMT2A (0.43) | KMT2ALMNAMEN1KDM4ETSHR | |
| SCHEMBL2429562 | 0.82 | MGLL (0.44) | KMT2ALMNAMEN1TRPM8MAPT | |
| SCHEMBL2425659 | 0.82 | MGLL (0.44) | KMT2ALMNAMEN1TRPM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | PFIZER INC. | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230493-A1 | 1-OXA-8-Azaspiro [4,5] Decabe-8-Carboxamide Compounds as FAAH Inhibitors | FAAH, FAAH2, FFAR1 | KMT2A 1419/4885LMNA 3357/4885MEN1 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.