Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111957 | 0.88 | SCN9A (0.44) | GPR119SCN9AMMP13CYP3A4 | |
| SCHEMBL15560717 | 0.81 | GPR119 (0.46) | GPR119MMP13CYP3A4CYP2C9 | |
| SCHEMBL16610232 | 0.81 | SCN9A (0.44) | GPR119SCN9AMMP13 | |
| Hydrochloric Acid SCHEMBL26911638 | 0.80 | HTR6 (0.56) | — | |
| SCHEMBL22776412 | 0.80 | SMARCA2 (0.47) | GPR119SCN9AMMP13 | |
| SCHEMBL1570643 | 0.79 | HTR6 (0.58) | SCN9A | |
| SCHEMBL15557373 | 0.78 | MMP13 (0.44) | GPR119MMP13 | |
| SCHEMBL15556996 | 0.78 | BRD4 (0.40) | GPR119MMP13 | |
| SCHEMBL17273480 | 0.76 | GPR119 (0.41) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL24330081 | 0.76 | SCN9A (0.45) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078971-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-04-21 | — | — | WO | disclosed |