Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17495521 | 0.82 | SCN9A (0.49) | SCN9APIK3CDALOX5APFEN1HPGDS | |
| SCHEMBL19404833 | 0.78 | SMN1; SMN2 (0.50) | HPGDSPOLBSMN1; SMN2PDE4BKDM4E | |
| SCHEMBL23791316 | 0.77 | HSD11B1 (0.52) | ALOX5APFEN1HPGDSPOLBSMN1; SMN2 | |
| SCHEMBL24330045 | 0.76 | GPR119 (0.45) | SCN9A | |
| SCHEMBL27510527 | 0.75 | DRD2 (0.58) | SCN9ASMN1; SMN2BRD3KDM4EMAPT | |
| SCHEMBL2283420 | 0.74 | PDE4B (0.51) | HPGDSPOLBSMN1; SMN2PDE4BKDM4E | |
| SCHEMBL19404832 | 0.74 | TRPV3 (0.52) | ALOX5APFEN1HPGDSPOLBSMN1; SMN2 | |
| SCHEMBL25431429 | 0.74 | PIK3CD (0.43) | PIK3CDALOX5APFEN1HPGDSPOLB | |
| SCHEMBL31208015 | 0.74 | PIK3CD (0.43) | PIK3CDALOX5APFEN1HPGDSPOLB | |
| SCHEMBL23625716 | 0.74 | SRC (0.44) | SCN9AALOX5APFEN1HPGDSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078971-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-04-21 | — | — | WO | disclosed |