Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469915 | 1.00 | SCN9A (0.34) | SCN9AKAT6APDE4DPDE4APDE4B | |
| SCHEMBL24333945 | 0.89 | PTGER1 (0.36) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29469650 | 0.89 | PTGER1 (0.36) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29469716 | 0.86 | HRH1 (0.35) | SCN9AKAT6ARORCMCHR1FABP4 | |
| SCHEMBL24334278 | 0.86 | HRH1 (0.35) | SCN9AKAT6ARORCMCHR1FABP4 | |
| SCHEMBL29469619 | 0.85 | RORC (0.34) | RORCMCHR1KCNH2 | |
| SCHEMBL24334422 | 0.85 | ALDH1A1 (0.34) | RORCMCHR1KCNH2 | |
| SCHEMBL29469646 | 0.85 | ALDH1A1 (0.34) | RORCMCHR1KCNH2 | |
| SCHEMBL24333795 | 0.82 | ALDH1A1 (0.36) | SCN9ARORCGPR6FABP4FABP5 | |
| SCHEMBL29469633 | 0.82 | ALDH1A1 (0.36) | SCN9ARORCGPR6FABP4FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |