Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469709 | 1.00 | FABP4 (0.38) | FABP4ALDH1A1HPGDMAPTGAA | |
| SCHEMBL31525463 | 0.92 | KAT6A (0.41) | ALDH1A1HPGDMAPTGAALMNA | |
| SCHEMBL24334004 | 0.87 | ALDH1A1 (0.34) | ALDH1A1HPGDMAPTGAALMNA | |
| SCHEMBL29469686 | 0.86 | NLRP3 (0.44) | — | |
| SCHEMBL24334273 | 0.86 | NLRP3 (0.44) | — | |
| SCHEMBL24333990 | 0.85 | MCOLN3 (0.41) | ALDH1A1HPGDMAPTGAALMNA | |
| SCHEMBL29469607 | 0.85 | KMT2A (0.41) | FABP4ALDH1A1HPGDMAPTGAA | |
| SCHEMBL24333973 | 0.85 | KMT2A (0.41) | FABP4ALDH1A1HPGDMAPTGAA | |
| SCHEMBL24333765 | 0.85 | USP2 (0.36) | ALDH1A1HPGDMAPTGAALMNA | |
| SCHEMBL24334461 | 0.84 | GHSR (0.41) | ALDH1A1HPGDMAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081807-A1 | SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER | THE BROAD INSTITUTE, INC. (US) | 2022-04-21 | — | — | WO | disclosed |