Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GHSR | Q92847 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910748 | 0.76 | GHSR (0.49) | HTR5ASLC2A1GHSR | |
| SCHEMBL14539452 | 0.72 | GHSR (0.59) | HTR5ASLC2A1GHSR | |
| SCHEMBL9875342 | 0.70 | FDPS (0.40) | FDPSCYP2D6LMNAGHSRCYP1A2 | |
| SCHEMBL9874777 | 0.70 | FDPS (0.40) | FDPSCYP2D6LMNAGHSRCYP1A2 | |
| SCHEMBL1177268 | 0.70 | MAPT (0.35) | KCNH2MAPT | |
| SCHEMBL9875371 | 0.68 | CYP2D6 (0.48) | FDPSCYP2D6LMNAGHSRCYP1A2 | |
| SCHEMBL18360656 | 0.65 | FDPS (0.34) | FDPSGHSR | |
| Trifluoroacetic Acid SCHEMBL27663777 | 0.65 | CHRNB2 (0.41) | FDPSLMNAMEN1TP53KMT2A | |
| SCHEMBL25562847 | 0.65 | FDPS (0.34) | FDPSGHSR | |
| SCHEMBL27476797 | 0.65 | FDPS (0.52) | FDPSCYP2D6LMNAGHSRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022064187-A1 | COMPOUNDS AS MODULATORS OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 (ERAP1) | Grey Wolf Therapeutics Limited (GB) | 2022-03-31 | — | — | WO | disclosed |