Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 11/20 | 0.53 |
| ▸ | FPR1 | P21462 | 10/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24093608 | 0.82 | ALOX5AP (0.39) | FPR2FPR1ALOX5APFEN1MEN1 | |
| SCHEMBL24045801 | 0.77 | MEN1 (0.53) | FPR2FPR1KDM1AMEN1LMNA | |
| SCHEMBL21319429 | 0.76 | FPR2 (0.54) | FPR2FPR1ALOX5APFEN1MEN1 | |
| SCHEMBL21341187 | 0.75 | L3MBTL1 (0.56) | FPR2FPR1L3MBTL1CDK1CDK2 | |
| SCHEMBL21899398 | 0.73 | FPR2 (0.54) | FPR2FPR1CDK1CDK2IRAK4 | |
| SCHEMBL13712974 | 0.71 | ALOX15 (0.50) | ALOX5APFEN1 | |
| SCHEMBL2737228 | 0.70 | HSD17B10 (0.48) | L3MBTL1CDK2MEN1LMNAKMT2A | |
| SCHEMBL21319255 | 0.70 | FPR2 (1.00) | FPR2FPR1 | |
| SCHEMBL12545906 | 0.67 | ALOX15 (0.49) | — | |
| SCHEMBL10094332 | 0.67 | L3MBTL1 (0.74) | L3MBTL1CDK1CDK2IRAK4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981767-A1 | PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | Bristol-Myers Squibb Company (US) | 2022-04-13 | — | — | EP | disclosed |
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |