SCHEMBL24045801

SCHEMBL24045801

CS(=O)(=O)Nc1ccccc1-c1ccc(N2CCCCC2=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
HPGD P15428 1/20 0.53
KMT2A Q03164 1/20 0.53
FPR2 P25090 17/20 0.52
FPR1 P21462 11/20 0.52
KDM1A O60341 1/20 0.48
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21899398 0.81 FPR2 (0.54) MEN1LMNAHPGDKMT2AFPR2
SCHEMBL24093571 0.78 RAB9A (0.53) MEN1LMNAHPGDKMT2AGFER
SCHEMBL24045805 0.77 KDM1A (0.47) FPR2FPR1KDM1A
SCHEMBL24337064 0.77 FPR2 (0.53) MEN1LMNAHPGDKMT2AFPR2
SCHEMBL24045765 0.75 FPR2 (0.48) LMNAHPGDFPR2GFER
SCHEMBL18955154 0.73 PIP4K2A (0.51) MEN1LMNAHPGDKMT2A
SCHEMBL21319429 0.73 FPR2 (0.54) MEN1LMNAHPGDKMT2AFPR2
SCHEMBL4533547 0.72 KDM1A (0.60) LMNAKMT2AKDM1A
SCHEMBL31645593 0.72 KDM1A (0.60) LMNAKMT2AKDM1A
SCHEMBL24045893 0.71 RAB9A (0.44) MEN1LMNAHPGDKMT2AGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3414227-B1 PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AND FORMYL PEPTIDE 1 RECEPTOR AGONISTS BRISTOL MYERS SQUIBB CO (US) 2021-11-24 EP disclosed