Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.33 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24656113 | 0.80 | HTT (0.41) | ALDH1A1HSD17B10ALOX15MAPK10HTT | |
| SCHEMBL8709873 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10ALOX15MAPK10HTT | |
| SCHEMBL523311 | 0.77 | GRIA1 (0.35) | ALDH1A1HSD17B10ILKKDM4EMAPK1 | |
| SCHEMBL1161458 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HTTKDM4EMEN1 | |
| SCHEMBL30174396 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HTTKDM4EMEN1 | |
| SCHEMBL24338007 | 0.75 | ILK (0.39) | ALDH1A1HSD17B10HTTILKKDM4E | |
| SCHEMBL29598381 | 0.72 | DPP4 (0.41) | ALDH1A1HSD17B10ILKKDM4EMAPK1 | |
| SCHEMBL1167126 | 0.72 | DPP4 (0.41) | ALDH1A1HSD17B10ILKKDM4EMAPK1 | |
| SCHEMBL29870122 | 0.70 | MET (0.43) | HTTKDM4ECBFBMAPTNPC1 | |
| SCHEMBL6520665 | 0.70 | MET (0.43) | HTTKDM4ECBFBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |