Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19567732 | 0.98 | ESR1 (0.42) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL20871917 | 0.98 | MEN1 (0.46) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL20871776 | 0.97 | MEN1 (0.44) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL22403499 | 0.97 | MEN1 (0.44) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL22403624 | 0.97 | MEN1 (0.44) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL10031186 | 0.94 | ESR1 (0.40) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL10031193 | 0.92 | ESR1 (0.39) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL19735410 | 0.92 | MEN1 (0.41) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL19735578 | 0.92 | MEN1 (0.41) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL12864073 | 0.91 | MEN1 (0.42) | ESR1ESR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-9416310-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-16 | — | — | US | disclosed |
| US-9139765-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9074128-B2 | Metal complexes having azaborol ligands and electronic device having the same | MERCK PATENT GMBH (DE) | 2015-07-07 | — | — | US | disclosed |
| US-8722898-B2 | — | — | 2014-05-13 | — | — | US | disclosed |
| US-20130046094-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| US-8361638-B2 | Fluorine derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120187349-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | US | disclosed |
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | MERCK PATENT GMBH (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120187349-A1 | MATERIALS FOR ELECTRONIC DEVICES | SLC26A3, SLCO4C1, SLCO2A1 | ESR1 116/4885ESR2 222/4885MAPT 1057/4885 |
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | ICOSLG, ERAL1, CTCF | ESR1 258/4885ESR2 876/4885MAPT 3424/4885 |
| US-20160240782-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, SLCO4C1, GJA1 | ESR1 79/4885ESR2 159/4885MAPT 578/4885 |
| US-20130046094-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | PIEZO1, L1CAM, OR10J3 | ESR1 243/4885ESR2 401/4885MAPT 1428/4885 |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | SLCO4C1, CTCF, AFF2 | ESR1 36/4885ESR2 198/4885MAPT 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.