SCHEMBL24340452

SCHEMBL24340452

CNCCCC[C@@H](C(=O)NC(C=O)C(C)O)N(C(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CSSC)NC(=O)CCc1ccc(Cl)cc1)c1ccc(C(N)=O)cc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ GRIA1 P42261 8/20 0.36
▸ FOLH1 Q04609 2/20 0.34
▸ NPY1R P25929 1/20 0.34
▸ NPY2R P49146 1/20 0.34
▸ NPY4R P50391 1/20 0.34
▸ NPY5R Q15761 1/20 0.34
▸ CTSL P07711 1/20 0.34
▸ CHRNA1 P02708 1/20 0.33
▸ CHRNG P07510 1/20 0.33
▸ CHRNB1 P11230 1/20 0.33
▸ CHRNB2 P17787 1/20 0.33
▸ CHRNB4 P30926 1/20 0.33
▸ CHRNA3 P32297 1/20 0.33
▸ CHRNA4 P43681 1/20 0.33
▸ GRIN1 Q05586 1/20 0.33
▸ CHRND Q07001 1/20 0.33
▸ GRIN2A Q12879 1/20 0.33
▸ GRM1 Q13255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24324990 0.84 NPY4R (0.42) GRIA1NPY1RNPY2RNPY4RNPY5R
SCHEMBL24325004 0.83 OPRD1 (0.42) GRIA1NPY1RNPY2RNPY4RNPY5R
SCHEMBL24325254 0.79 NPY4R (0.40) GRIA1NPY1RNPY2RNPY4RNPY5R
SCHEMBL24324757 0.78 NPY4R (0.41) GRIA1NPY1RNPY2RNPY4RNPY5R
SCHEMBL24324744 0.78 OPRM1 (0.41) NPY1RNPY2RNPY4RNPY5R
SCHEMBL24324775 0.78 NPY4R (0.40) NPY1RNPY2RNPY4RNPY5R
SCHEMBL24324967 0.78 NPY4R (0.53) NPY1RNPY2RNPY4RNPY5R
SCHEMBL24324995 0.77 OPRM1 (0.41) GRIA1NPY1RNPY2RNPY4RNPY5R
SCHEMBL24325348 0.76 GRIA1 (0.43) GRIA1NPY1RNPY2RNPY4RNPY5R
SCHEMBL24340683 0.72 OPRM1 (0.43) GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same CDRD VENTURES INC. (CA) 2022-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279732-B2 Somatostatin receptor antagonist compounds and methods of using the same GPR119, SSTR5, SSTR2 GRIA1 284/4885FOLH1 528/4885NPY1R 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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