SCHEMBL24324995

SCHEMBL24324995

CSC(=O)NC[C@@H](NC(=O)CCc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N(c1ccc(C(N)=O)cc1)[C@@H](CCCCN)C(=O)NC(C(=O)NCC(=O)N[C@H](Cc1ccc(O)cc1)C(N)=O)C(C)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.41
▸ OPRD1 P41143 4/20 0.41
▸ OPRK1 P41145 3/20 0.41
▸ IL23R Q5VWK5 11/20 0.36
▸ OXTR P30559 1/20 0.36
▸ NPBWR1 P48145 1/20 0.35
▸ NPY1R P25929 1/20 0.35
▸ NPY2R P49146 1/20 0.35
▸ NPY4R P50391 1/20 0.35
▸ NPY5R Q15761 1/20 0.35
▸ GRIA1 P42261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24324744 0.91 OPRM1 (0.41) OPRM1OPRD1OPRK1IL23ROXTR
SCHEMBL24325004 0.86 OPRD1 (0.42) OPRM1OPRD1OPRK1IL23ROXTR
SCHEMBL20715848 0.85 NPY4R (0.46) IL23RNPBWR1NPY1RNPY2RNPY4R
SCHEMBL20715581 0.82 OPRM1 (0.51) OPRM1OPRD1OPRK1IL23RNPBWR1
SCHEMBL20715782 0.80 OPRM1 (0.51) OPRM1OPRD1OPRK1IL23RNPBWR1
SCHEMBL20715847 0.80 OPRM1 (0.51) OPRM1OPRD1OPRK1IL23RNPBWR1
SCHEMBL19234644 0.77 KISS1R (0.45) OPRM1OPRD1OPRK1NPY1RNPY2R
SCHEMBL24340452 0.77 GRIA1 (0.36) NPY1RNPY2RNPY4RNPY5RGRIA1
SCHEMBL24341151 0.77 OPRM1 (0.46) OPRM1OPRD1OPRK1IL23ROXTR
SCHEMBL20715790 0.76 OPRM1 (0.47) OPRM1OPRD1OPRK1IL23ROXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME CDRD VENTURES INC. (CA) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112242-A1 SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME GPR119, SSTR5, SSTR2 OPRM1 1008/4885OPRD1 1890/4885OPRK1 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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