Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24930 | 0.79 | LMNA (0.62) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL67041 | 0.78 | CCR1 (0.64) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL2016968 | 0.78 | MAPT (0.64) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL8313 | 0.77 | LMNA (1.00) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL6513577 | 0.77 | LMNA (1.00) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL2519517 | 0.77 | KDM4E (0.50) | LMNAKDM4EERN1CYP1A2 | |
| Pyrazine SCHEMBL28719971 | 0.77 | LMNA (0.89) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL7142651 | 0.76 | LMNA (0.96) | LMNAMAPTKDM4ECYP3A4HTT | |
| Iodide SCHEMBL10638043 | 0.76 | LMNA (0.96) | LMNAMAPTKDM4ECYP3A4HTT | |
| SCHEMBL15788918 | 0.76 | LMNA (0.96) | LMNAMAPTKDM4ECYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49118-E1 | Material for organic electroluminescence device and electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2022-06-28 | — | — | US | claimed |
| CN-112390811-B | Dithia-anthrone derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-03-04 | — | — | CN | claimed |
| CN-114057711-A | Anthracene ketone spiro derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2022-02-18 | — | — | CN | claimed |
| CN-107556298-B | Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element | 出光兴产株式会社 | 2021-12-21 | — | — | CN | claimed |
| CN-107586290-B | Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element | 出光兴产株式会社 | 2021-05-11 | — | — | CN | claimed |
| CN-112390811-A | Dithia-anthrone derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-02-23 | — | — | CN | claimed |
| US-10550203-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2020-02-04 | — | — | US | claimed |
| CN-110551054-A | maleimide derivative, and preparation method and application thereof | TECHNICAL INST PHYSICS & CHEMISTRY CAS | 2019-12-10 | — | — | CN | claimed |
| US-10283717-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-07 | — | — | US | claimed |
| US-20180319905-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-11-08 | — | — | US | claimed |
| EP-1913011-A2 | OLIGONUCLEOTIDES COMPRISING A LIGAND TETHERED TO A MODIFIED OR NON-NATURAL NUCLEOBASE | Alnylam Pharmaceuticals Inc. (US) | 2008-04-23 | — | — | EP | claimed |
| US-20080076903-A1 | DATA STORAGE MEDIUM AND METHOD FOR HIGH DENSITY DATA STORAGE | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2008-03-27 | — | — | US | claimed |
| EP-1789553-A2 | OLIGONUCLEOTIDES COMPRISING A NON-PHOSPHATE BACKBONE LINKAGE | Alnylam Pharmaceuticals Inc. (US) | 2007-05-30 | — | — | EP | claimed |
| EP-1768998-A2 | SINGLE-STRANDED AND DOUBLE-STRANDED OLIGONUCLEOTIDES COMPRISING A 2-ARYLPROPYL MOIETY | Alnylam Pharmaceuticals Inc. (US) | 2007-04-04 | — | — | EP | claimed |
| EP-1750776-A2 | OLIGONUCLEOTIDES COMPRISING A C5-MODIFIED PYRIMIDINE | Alnylam Pharmaceuticals Inc. (US) | 2007-02-14 | — | — | EP | claimed |
| WO-2006112872-A2 | OLIGONUCLEOTIDES COMPRISING A LIGAND TETHERED TO A MODIFIED OR NON-NATURAL NUCLEOBASE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2006-10-26 | — | — | WO | claimed |
| WO-2006088490-A2 | OLIGONUCLEOTIDES COMPRISING A NON-PHOSPHATE BACKBONE LINKAGE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2006-08-24 | — | — | WO | claimed |
| WO-2006078278-A2 | SINGLE-STRANDED AND DOUBLE-STRANDED OLIGONUCLEOTIDES COMPRISING A 2-ARYLPROPYL MOIETY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | WO | claimed |
| WO-2006073458-A2 | OLIGONUCLEOTIDES COMPRISING A C5-MODIFIED PYRIMIDINE | ALNYLAM PHARMACEUTICALS, INC. (US) | 2006-07-13 | — | — | WO | claimed |
| US-20050288244-A1 | Oligonucleotides comprising a C5-modified pyrimidine | ALNYLAM PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10283717-B2 | Organic electroluminescent device using aryl amine derivative containing heterocycle | SLC18A1, SLC18A2, AOC2 | LMNA 3089/4885MAPT 2683/4885KDM4E 2498/4885 |
| US-20050288244-A1 | Oligonucleotides comprising a C5-modified pyrimidine | DUT, TYMP, DPYD | LMNA 4061/4885MAPT 4345/4885KDM4E 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.