SCHEMBL2434448

SCHEMBL2434448

CCCCc1ccc2c(c1)-c1ccccc1[PH](=O)O2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.38
PSMB5 P28074 1/20 0.38
METAP2 P50579 1/20 0.35
SKP2 Q13309 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
RORA P35398 1/20 0.33
RORC P51449 1/20 0.33
RORB Q92753 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
DHODH Q02127 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
LPL P06858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431079 0.86 GPR3 (0.41) GPR3PSMB5METAP2SKP2CA2
SCHEMBL2435389 0.86 SMN1; SMN2 (0.46) ALDH1A1MAPK1NPC1LMNAMAPT
SCHEMBL2431664 0.76 CNR2 (0.46)
SCHEMBL2436397 0.75 ELANE (0.42) ALDH1A1HSD17B10KDM4EGAALMNA
Alcohol SCHEMBL28762611 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL2434447 0.73 HDAC4 (0.35) ALDH1A1HPGDHSD17B10GAANPC1
SCHEMBL2436972 0.72 NR1H2 (0.37) LIPGTHRATHRB
SCHEMBL2441281 0.72 GPR3 (0.35) GPR3PSMB5SKP2CA1CA2
SCHEMBL30781 0.72 HSP90AA1 (0.35) MAPK1KDM4E
SCHEMBL29363087 0.72 HSP90AA1 (0.35) MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed