Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344489 | 0.86 | PAX8 (0.34) | PAX8KCNQ3KCNQ2 | |
| SCHEMBL24344233 | 0.85 | KCNQ3 (0.32) | KCNQ3KCNQ2 | |
| SCHEMBL24344488 | 0.73 | HSD17B10 (0.33) | PAX8 | |
| SCHEMBL22509297 | 0.72 | PAX8 (0.39) | PAX8 | |
| SCHEMBL26978141 | 0.71 | ALDH1A1 (0.36) | KCNQ3KCNQ2 | |
| SCHEMBL24343977 | 0.71 | KCNQ3 (0.32) | KCNQ3KCNQ2 | |
| SCHEMBL17467163 | 0.70 | PAX8 (0.38) | PAX8IRAK4 | |
| SCHEMBL15587354 | 0.70 | PAX8 (0.38) | PAX8IRAK4 | |
| SCHEMBL24344487 | 0.69 | ALDH1A1 (0.43) | — | |
| SCHEMBL7999363 | 0.68 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |