SCHEMBL24344945

SCHEMBL24344945

c1ccc(-n2c3ccccc3c3ccc(-c4cc5ccc6cc(-c7ccc(-c8ccccn8)nc7)cc7ccc(c4)c5c67)cc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPGDS O60760 1/20 0.36
METAP2 P50579 2/20 0.35
KHK P50053 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPY5R Q15761 1/20 0.33
DHODH Q02127 1/20 0.33
MAT2A P31153 1/20 0.32
MCL1 Q07820 1/20 0.32
ALOX5AP P20292 1/20 0.32
GRM5 P41594 2/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24345161 0.86 CYP19A1 (0.42) KDM4EATML3MBTL1METAP2DHODH
SCHEMBL16303007 0.85 HPGDS (0.35) KDM4EHPGDSMETAP2ALDH1A1TSHR
SCHEMBL14728159 0.84 KDM4E (0.41) KDM4EATML3MBTL1HPGDSMETAP2
SCHEMBL21190466 0.83 L3MBTL1 (0.56) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL24626174 0.83 L3MBTL1 (0.39) KDM4EATML3MBTL1HPGDSALDH1A1
SCHEMBL24626321 0.83 L3MBTL1 (0.39) KDM4EATML3MBTL1HPGDSALDH1A1
SCHEMBL24626123 0.83 L3MBTL1 (0.39) KDM4EATML3MBTL1HPGDSALDH1A1
SCHEMBL16726757 0.82 KDM4E (0.43) KDM4EATML3MBTL1METAP2ALDH1A1
SCHEMBL16726776 0.82 KDM4E (0.43) KDM4EATML3MBTL1METAP2ALDH1A1
SCHEMBL23081858 0.81 HPGDS (0.41) KDM4EATML3MBTL1HPGDSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230145851-A1 INTERFACE LAYER DESIGN FOR EFFICIENT AND STABLE WHITE OLEDS UNITED STATES DEPARTMENT OF ENERGY 2023-05-11 US disclosed
US-20230145851-A1 INTERFACE LAYER DESIGN FOR EFFICIENT AND STABLE WHITE OLEDS UNITED STATES DEPARTMENT OF ENERGY 2023-05-11 US disclosed
US-20220102641-A1 FUNCTIONAL MATERIALS FOR OLED APPLICATIONS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2022-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220102641-A1 FUNCTIONAL MATERIALS FOR OLED APPLICATIONS OCIAD1, OGFOD1, SLCO1A2 KDM4E 4188/4885ATM 3083/4885L3MBTL1 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.