Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24348336 | 0.81 | HSD11B1 (0.37) | PTPN11LMNASMN1; SMN2HSD17B10HSD11B1 | |
| SCHEMBL24348356 | 0.68 | PTPN11 (0.43) | PTPN11LMNASMN1; SMN2POLB | |
| SCHEMBL1015076 | 0.65 | HSD11B1 (0.57) | PTPN11SMN1; SMN2HSD17B10HSD11B1KMT2A | |
| SCHEMBL24349015 | 0.63 | VNN1 (0.37) | MAPTHSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL14344846 | 0.63 | LMNA (0.53) | MAPTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL26550880 | 0.63 | TMEM97 (0.38) | MAPTLMNASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL8261413 | 0.62 | LMNA (0.52) | MAPTLMNASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL6663539 | 0.61 | — | — | |
| SCHEMBL10498542 | 0.61 | LMNA (0.70) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1919434 | 0.60 | MEN1 (0.73) | HSD17B10MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053803-A1 | HERBICIDAL PYRIMIDINE DERIVATIVES | MOA Technology Limited (GB) | 2022-03-17 | — | — | WO | disclosed |