Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.52 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GUSB | P08236 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820143 | 0.76 | RAB9A (0.66) | ANO1ANO2TP53GUSBNPC1 | |
| SCHEMBL28139056 | 0.76 | ELANE (0.69) | ANO1ANO2TP53ELANEHTT | |
| SCHEMBL29051297 | 0.72 | MAOB (0.42) | TP53NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL6452343 | 0.71 | RAB9A (0.63) | TP53USP2NPC1RAB9ANPSR1 | |
| SCHEMBL6451219 | 0.71 | HPGD (0.54) | ANO1ANO2TP53ELANEGUSB | |
| SCHEMBL12368393 | 0.71 | MAOB (0.64) | ALDH1A1HPGDTSHR | |
| SCHEMBL15157619 | 0.70 | ALDH1A1 (0.67) | USP2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6450847 | 0.70 | RAB9A (0.64) | TP53NPC1RAB9ANPSR1L3MBTL1 | |
| SCHEMBL11816106 | 0.70 | RAB9A (0.72) | ANO1ANO2TP53GUSBNPC1 | |
| SCHEMBL3985729 | 0.70 | AHR (0.59) | TP53NPC1RAB9ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274074-B2 | Pharmaceutical composition for ANO1 antagonist with anticancer activity | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274074-B2 | Pharmaceutical composition for ANO1 antagonist with anticancer activity | ANO1, ANO2, TMEM109 | ANO1 1/4885ANO2 2/4885TP53 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.