SCHEMBL2434890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2430551	0.94	BRDT (0.39)	ADORA3CACNA2D1BRDTMTNR1AMTNR1B
	SCHEMBL2429157	0.86	SIK1 (0.39)	ADORA3BRDTMTNR1AMTNR1BCYP1A2
	SCHEMBL2432159	0.85	NPC1 (0.37)	RAB9ASMN1; SMN2MEN1LMNAMAPT
	SCHEMBL1136104	0.82	PDE4D (0.37)	ADORA3BRDTMTNR1AMTNR1BSIK1
	SCHEMBL2430337	0.81	PDE5A (0.40)	SMN1; SMN2KMT2APDE4BALDH1A1AR
	SCHEMBL1136159	0.81	MAOB (0.36)	BRDTMTNR1AMTNR1BCDK4CCND1
	SCHEMBL1136089	0.80	PDE4D (0.36)	ADORA3SMN1; SMN2MEN1LMNAMAPT
	SCHEMBL2434674	0.80	HDAC4 (0.40)	BRDTMTNR1AMTNR1BSMN1; SMN2LMNA
	SCHEMBL1136151	0.80	ADORA3 (0.44)	ADORA3CACNA2D1BRDTCTSGKLK7
	SCHEMBL1135964	0.79	MAOB (0.39)	BRDTMTNR1AMTNR1BCDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.