SCHEMBL2434674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2429157	0.92	SIK1 (0.39)	BRDTMTNR1AMTNR1BPDE4ACDK4
	SCHEMBL1136189	0.91	MAOB (0.37)	HDAC4HDAC2HDAC8BRDTMTNR1A
	SCHEMBL2433158	0.88	ALDH1A1 (0.39)	SMN1; SMN2KDM4EHSD17B10LMNAMAPT
	SCHEMBL2432838	0.85	HTR7 (0.42)	PDE4AHTTSMN1; SMN2KDM4EPDE4B
	SCHEMBL2434710	0.85	KDM4E (0.44)	HDAC4HDAC2HDAC8CNR1CNR2
	SCHEMBL2430551	0.84	BRDT (0.39)	BRDTMTNR1AMTNR1BKDM4EPDE4B
	SCHEMBL1136104	0.83	PDE4D (0.37)	BRDTMTNR1AMTNR1BKDM4EPDE4D
	SCHEMBL1135964	0.82	MAOB (0.39)	BRDTMTNR1AMTNR1BCDK4CCND1
	SCHEMBL2434676	0.81	MAPT (0.37)	PDE4ASMN1; SMN2PDE4BTSHRLMNA
	SCHEMBL1136159	0.80	MAOB (0.36)	BRDTMTNR1AMTNR1BCDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.