Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312596 | 0.84 | LTA4H (0.50) | LTA4HCASP6CYP1A2CYP2D6MAPT | |
| SCHEMBL24352277 | 0.75 | LTA4H (0.45) | LTA4HCASP6CYP1A2CYP2D6MAPT | |
| SCHEMBL24352628 | 0.75 | CYP1A2 (0.48) | LTA4HCYP1A2CYP2D6MAPTCYP3A4 | |
| SCHEMBL28133533 | 0.72 | CYP1A2 (0.50) | CASP6CYP1A2CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL24352624 | 0.72 | CYP1A2 (0.47) | LTA4HCYP1A2CYP2D6MAPTCYP3A4 | |
| SCHEMBL22910530 | 0.71 | LTA4H (0.47) | LTA4HCASP6CYP1A2MAPTALDH1A1 | |
| SCHEMBL22910534 | 0.69 | LTA4H (0.53) | LTA4HSLC6A2SLC6A4SLC6A3CD274 | |
| SCHEMBL20657047 | 0.68 | SMN1; SMN2 (0.46) | CASP6MAPTALDH1A1HPGDTSHR | |
| SCHEMBL404300 | 0.68 | PBRM1 (0.47) | CASP6MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL403090 | 0.68 | LDHA (0.47) | CYP1A2CYP2D6CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | LTA4H 3035/4885CASP6 2981/4885CYP1A2 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.