Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24352736 | 0.85 | CASP6 (0.42) | CASP6PDE9AHTR2CHTR2AHTR2B | |
| SCHEMBL24352816 | 0.83 | CASP6 (0.39) | CASP6PDE9AHTR2CHTR2AHTR2B | |
| SCHEMBL22910530 | 0.79 | LTA4H (0.47) | LTA4HCASP6PDE9AKDM4EMAPT | |
| SCHEMBL28680308 | 0.78 | HTR2C (0.40) | CASP6PDE9AHTR2CHTR2AHTR2B | |
| SCHEMBL24352663 | 0.77 | DPP4 (0.47) | CASP6PDE9AHTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL29473282 | 0.76 | DPP4 (0.46) | CASP6PDE9AHTR2CHTR2AHTR2B | |
| SCHEMBL24352409 | 0.75 | LTA4H (0.44) | LTA4HCASP6SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL31019977 | 0.75 | LTA4H (0.44) | LTA4HHTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL24352491 | 0.75 | CASP6 (0.41) | CASP6HTR2CHTR2AHTR2BKDM4E | |
| SCHEMBL24352771 | 0.74 | KCNA5 (0.51) | CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119395-A1 | BICYCLIC COMPOUNDS | SLC10A1, PKD1, CYP11B2 | LTA4H 3035/4885CASP6 2981/4885PDE9A 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.