SCHEMBL2427405

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136338	0.88	SIK1 (0.42)	SIK1SIK2SIK3GABRA1GABRG2
	SCHEMBL2434167	0.81	PIM1 (0.43)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL2430093	0.78	IDO1 (0.40)	MAOBMAOAKDRSIRT5FLT4
	SCHEMBL2435152	0.76	KDM4E (0.43)	MAOBMAOATUBB4ATUBBTUBA3C
	SCHEMBL2434369	0.75	HTR1A (0.40)	IDO1ALDH1A1MAPTKMT2A
	SCHEMBL2428272	0.75	ALDH1A1 (0.43)	MAOBKDRFLT4NPC1RAB9A
	SCHEMBL2521643	0.74	CCNE1 (0.35)	SIK1SIK2SIK3TUBB4ATUBB
	SCHEMBL2432485	0.74	HTR1A (0.39)	IDO1ALDH1A1MAPTMEN1KMT2A
	SCHEMBL2432794	0.73	MAPT (0.39)	IDO1ALDH1A1MAPTMEN1KMT2A
	SCHEMBL2432159	0.73	NPC1 (0.37)	KDRSIRT5NPC1RAB9AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.